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Dr Richard Clarkson

Dr Richard ClarksonResearch Institution: Cardiff University

Award: £132,000   Duration: 3 years

Project Title: Unlocking oncogene dependent cell death in pancreatic tumours

Project Aims: Normal cells are programmed to die if they become damaged or diseased in a process called apoptosis, but pancreatic cancer cells contain a molecule called c-FLIP which stalls this process. Dr Clarkson has shown in laboratory tests that blocking c-FLIP from working 'releases the brakes' on the anti-tumour process. He now wants to see if this works in mice with pancreatic tumours and will test new ways to block c-FLIP.