Skip Content

PCRF-funded research projects

All the research we support is funded entirely by public donations. To date, twenty seven projects have been funded with a total value of £4 million. These are focused on an early diagnostic test and the development and monitoring of new treatments.

 

 Grants made in 2012 Award Round

Professor Caroline Dive

Principal Applicant: Professor Caroline Dive
Institution: Paterson Institute for Cancer Research

Project Title: Development of blood-borne biomarkers for improving treatment selection for pancreatic cancer patients More information...
Watch the video

Professor Lindy Durrant

Pricipal Applicant: Professor Lindy Durrant
Institution:
The University of Nottingham

Project Title: Characterisation of novel anti-glycan mAbs targeting pancreatic cancer More information...

Dr Thorsten Hagemann

Principal Applicant: Prof Thorsten Hagemann
Institution: Centre for Cancer & Inflammation, Barts Cancer Institute

Project Title: Defining the role of regulatory B cells in pancreatic cancer More information...

Dr John Marshall

Principal Applicant: Dr. John Marshall
Institution: Centre for Tumour Biology, Barts Cancer Institute 

Project Title: Using Transgenic Mouse Models to Develop Integrin avb6-Targeted Therapy of Pancreatic Cancer More information...

Dr Stephen Pereira

Principal Applicant: Dr. Stephen Pereira
Institution: UCL Institute of Hepatology

Project Title: Targeting tumour metabolomics: a novel strategy for the diagnosis and treatment of pancreatic carcinoma More information...
Watch the video

Dr Yaohe Wang

Principal Applicant: Dr. Yaohe Wang
Institution: Barts Cancer Institute

Project Title: Development of a Novel Therapy for Pancreatic Cancer using Lister Strain Vaccinia Virus Armed with a Hypoxia-Regulated Immunostimulatory Gene, Interleukin-12 More information...

 

 Grants made in 2011 Award Round

 Eithne Costello

Principal Applicant: Dr. Eithne Costello
Institution: University of Liverpool

Project Title: Involvement of microRNAs in the activation of cancer-associated pancreatic stellate cells. More information...

 Prof Marco Falasca

Principal Applicant: Professor Marco Falasca
Institution: Blizard Institute of Cell and Molecular Science, Barts and The London 

Project Title: ABC transporters autocrine loop inhibition to treat pancreatic cancer. More information...

 Gunnel Hallden


Principal Applicant: Dr. Gunnel Halldén
Institution: Centre for Molecular Oncology and Imaging, Barts Cancer Institute

Project Title: Improved virotherapy for integrin-expressing pancreatic cancers. More information...

 Prof Nick Lemoine


Principal Applicant: Professor Nick Lemoine
Institution: Barts Cancer Institute, Queen Mary University of London

Project Title: Evaluation of the role of ΔNp63α in a new transgenic mouse model that mimics a highly aggressive subtype of human pancreatic cancer. More information...   
Watch the video

Prof Stephen Neidle


Principal Applicant:
Professor Stephen Neidle
Institution: The School of Pharmacy, University of London

Project Title: The design and development of novel agents for the treatment of chemoresistant pancreatic cancer. More information...
Watch the video...

 

Grants made in 2010 Award Round

Professor Marco Falasca

Principal Applicant: Professor Marco Falasca
Institution: Blizard Institute of Cell and Molecular Science, Barts and The London

Project Title: Identification of potential novel therapeutic agents for pancreatic cancer. 

 Professor Anthony Magee Principal Applicant: Professor Anthony Magee
Institution:Imperial College London


Project Title:
 Hedgehog acyltransferase: a potential therapeutic target in pancreatic cancer. More information...
Watch the video...

 Professor Jeff Evans

Principal Applicant: Professor Jeff Evans
Institution: University of Glasgow

Project Title: In vivo evaluation of Src kinase inhibition as adjuvant therapy following pancreatic cancer resection. More information...
Watch the video...

 Dr. Thorsten Hagemann


Principal Applicant: Dr Thorsten Hagemann
Institution: Centre for Cancer & Inflammation, Barts Cancer Institute

Project Title: Enhancing oncolytic adenovirus efficacy in pancreatic cancer by switching tumour-associated macrophages. More information...
Watch the video

 Dr. Claire Wells

Principal Applicant: Dr Claire Wells
Institution: Kings College London

Project Title: PAK family kinases in pancreatic cancer – a study of therapeutic potential. More information...
Watch the video...

 

Grants made in 2009 Award Round

Dr. Gunnel Hallden

Principal Applicant: Dr. Gunnel Halldén
Institution: Centre for Molecular Oncology and Imaging, Barts Cancer Institute

Project Title: Targeting pancreatic cancer with oncolytic virotherapy and cytotoxic drugs. More information... 
Watch the video...

Mr. Hemant Kocher

Principal Applicant: Mr. Hemant Kocher
Institution: Centre for Tumour Biology, Barts Cancer Institute

Project Title: FGF Signalling in pancreatic cancer. More information... 
Watch the video...

Professor Lindy Durrant

Principal Applicant: Professor Lindy Durrant
Institution: University of Nottingham, Academic Clinical Oncology

Project Title: Glycolipids as targets for therapeutic anti-tumour monoclonal antibodies for treatment of pancreatic cancer. More information... 
Watch the video...

Dr. Yaohe Wang

Principal Applicant: Dr. Yaohe Wang
Institution: Centre for Molecular Oncolgy and Imaging, Barts Cancer Institute

Project Title: Novel therapy for pancreatic cancer using a Lister strain vaccinia virus armed with Interleukin-10. More information... 
Watch the video...

Professor Marco Falasca

Principal Applicant: Professor Marco Falasca
Institution: Blizard Institute of Cell and Molecular Science, Barts and The London

Project Title: Investigation of mechanisms regulating phosphoinositide 3-kinase expression in pancreatic cancer. More information...
Watch the video...

 

Grants made in 2008 Award Round

Dr. Tanja Crnogorac-Jurcevic

Principal Applicant: Dr. Tatjana Crnogorac-Jurcevic
Institution: Centre for Molecular Oncology and Imaging, Barts Cancer Institute

Project Title: Discovery and validation of urinary peptides for non-invasive diagnosis of pancreatic cancer. More information... 
Watch the video...

Dr. Azeem Saleem

Principal Applicant: Dr. Azeem Saleem
Institution: University of Manchester, Academic Radiation Oncology

Project Title: Pilot study to evaluate the pathological basis and utility of FLT-PET/CT and FDG-PET/CT in therapy development in pancreatic cancer. More information... 
Watch the video...

Dr. John Marshall

Principal Applicant: Dr. John Marshall
Institution: Centre for Tumour Biology, Barts Cancer Institute  

Project Title: Development of imaging and therapy of pancreatic cancer by targeting the integrin αvβ6. More information...
Watch the video...

Professor Marco Falasca

Principal Applicant: Professor Marco Falasca
Institution: Blizard Institute of Cell and Molecular Science, Barts and The London

Project Title: Role of phosphoinositide 3-kinase class ΙB in human pancreatic cancer. More information... 
Watch the video...

 

Grants made in 2007 Award Round

Dr. Eithne Costello

Principal Applicant: Dr. Eithne Costello
Institution: University of Liverpool - Division of Surgery & Oncology

Project Title: Crosstalk between pancreatic cancer cells and tumour infiltrating monocytes: role in invasion and potential for therapeutic exploitation. More information... 
Watch the video...

 

Grants made in 2006 Award Round

Dr. Tatjana Crnogorac-Jurcevic

Principal Applicant: Dr. Tatjana Crnogorac-Jurcevic
Institution: Centre for Molecular Oncology and Imaging, Barts Cancer Institute

Project Title: The role of S100PBPR in early pancreatic cancer development. More information...