Project Title: Understanding and targeting c-Met
endosomal signalling in pancreatic cancer
Project Aims: A molecule known as c-Met is believed to help trigger pancreatic cancer to spread, but current drugs designed to ‘switch off’ c-Met may well cause resistance, as experienced with similar types of drugs. However, Dr Kermorgant and her team recently discovered evidence which shed new light on how c-Met functions, and they will use this information to test out different drug compounds which could prevent the molecule from working