Researching the cures


Professor John Marshall

Professor Marshall’s previous PRCF-funded research showed that the molecule alpha-v beta-6 (αvβ6),  which is abundant in around 80% of pancreatic cancers, drives the spread of the cancer to other organs. This new project will examine how αvβ6 causes the cancer to spread and will test two different types of drugs that he has been developing to stop αvβ6 working, and determine when and how best they could potentially be used for patients.

Project Title: The integrin αvβ6drives PDAC metastasis: mechanisms and therapeutic insights