Researching the cures

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Research projects

All the research we support is funded entirely by public donations. To date, 61 projects have been funded, with a total value of over £13 million. These are focused on early diagnosis of pancreatic cancer and the development and monitoring of new treatments.

Hemant Kocher and Richard Grose

Prof Hemant Kocher and Dr Richard Grose

Grant made in 2014 Award Round

This research looks at ways to block the chemical messaging between pancreatic cancer cells and stellate cells which helps the cancer to invade neighbouring healthy tissue.

Stephanie Kermorgant

Dr Stephanie Kermorgant

Grant made in 2014 Award Round

Dr Kermorgant is investigating drug compounds that could curb the action of a molecule called c-Met, which triggers the spread of pancreatic cancer.

Dr Patrick Forde

Dr Patrick Forde

Grant made in 2014 Award Round

Dr Forde is evaluating the potential for short electric pulses to increase the uptake of chemotherapy drugs by pancreatic cancer cells.

Dr Jason Bruce

Dr Jason Bruce

Grant made in 2014 Award Round

Dr Bruce is exploring ways to cut off the energy supply used by pancreatic cancer cells to pump calcium out of the cells.

Professor Yaohe Wang

Dr Yaohe Wang

Grant made in 2012 Award Round

Dr Wang is investigating whether the Vaccinia virus - used against smallpox - can be engineered for use against pancreatic cancer.

Steve Pereira

Dr Stephen Pereira

Grant made in 2012 Award Round

This project focuses on two enzymes which help cancer cells produce energy. The aim is to see if these can be used as a biomarker to diagnose and predict the aggressiveness of the tumour.

Professor John Marshall

Professor John Marshall

Grant made in 2012 Award Round

This project builds on previous PCRF-funded research into blocking the action of molecule - called avb6 - which allows pancreatic cancer cells to invade healthy tissues more easily.

Professor Lindy Durrant

Professor Lindy Durrant

Grant made in 2012 Award Round

Professor Durrant is engineering antibodies that bind to sugars found on the surface of tumours, stimulating an immune response.

Caroline Manchester

Professor Caroline Dive

Grant made in 2012 Award Round

Professor Dive is analysing pancreatic cancer cells circulating in the blood. The aim is to develop a profiling technique using blood samples.

Stephen Neidle

Professor Stephen Neidle

Grant made in 2011 Award Round

In this project, Professor Neidle and his team aim to optimise a drug that they have developed to target a crucial cancer enzyme called telomerase.