Researching the cures

Donate

Research projects

All the research we support is funded entirely by public donations. To date, 68 projects have been funded, with a total value of over £14.5 million. These are focused on early diagnosis of pancreatic cancer and the development and monitoring of new treatments.

Professor Yaohe Wang

Dr Yaohe Wang

Grant made in 2012 Award Round

Dr Wang is investigating whether the Vaccinia virus - used against smallpox - can be engineered for use against pancreatic cancer.

Steve Pereira

Dr Stephen Pereira

Grant made in 2012 Award Round

This project focuses on two enzymes which help cancer cells produce energy. The aim is to see if these can be used as a biomarker to diagnose and predict the aggressiveness of the tumour.

Professor John Marshall

Professor John Marshall

Grant made in 2012 Award Round

This project builds on previous PCRF-funded research into blocking the action of molecule - called avb6 - which allows pancreatic cancer cells to invade healthy tissues more easily.

Professor Lindy Durrant

Professor Lindy Durrant

Grant made in 2012 Award Round

Professor Durrant is engineering antibodies that bind to sugars found on the surface of tumours, stimulating an immune response.

Caroline Manchester

Professor Caroline Dive

Grant made in 2012 Award Round

Professor Dive is analysing pancreatic cancer cells circulating in the blood. The aim is to develop a profiling technique using blood samples.

Stephen Neidle

Professor Stephen Neidle

Grant made in 2011 Award Round

In this project, Professor Neidle and his team aim to optimise a drug that they have developed to target a crucial cancer enzyme called telomerase.

Nick Lemoine

Professor Nick Lemoine

Grant made in 2011 Award Round

Professor Lemoine is studying the effects of a specific gene found in a particularly aggressive form of pacnreatic cancer.

Gunnel Hallden

Dr Gunnel Halldén

Grant made in 2011 Award Round

Dr Halldén is investigating how a virotherapy developed in her team could work in combination with other drugs to kill cancer cells.

Marco Falasca

Professor Marco Falasca

Grant made in 2011 Award Round

This project will evaluate whether two clinically-approved drugs could be used against ABC molecules. This family of molecules is thought to be involved in the process through which cancer cells stimulate their own growth.

Eithne Costello

Dr Eithne Costello

Grant made in 2011 Award Round

Dr Costello's team is exploring the role of microRNAs - molecules thought to help prevent stellate cells from forming protective barriers around tumours.