Researching the cures

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Research projects

All the research we support is funded entirely by public donations. To date, 61 projects have been funded, with a total value of over £13 million. These are focused on early diagnosis of pancreatic cancer and the development and monitoring of new treatments.

Nick Lemoine

Professor Nick Lemoine

Grant made in 2011 Award Round

Professor Lemoine is studying the effects of a specific gene found in a particularly aggressive form of pacnreatic cancer.

Gunnel Hallden

Dr Gunnel Halldén

Grant made in 2011 Award Round

Dr Halldén is investigating how a virotherapy developed in her team could work in combination with other drugs to kill cancer cells.

Marco Falasca

Professor Marco Falasca

Grant made in 2011 Award Round

This project will evaluate whether two clinically-approved drugs could be used against ABC molecules. This family of molecules is thought to be involved in the process through which cancer cells stimulate their own growth.

Eithne Costello

Dr Eithne Costello

Grant made in 2011 Award Round

Dr Costello's team is exploring the role of microRNAs - molecules thought to help prevent stellate cells from forming protective barriers around tumours.

Claire Wells

Dr Claire Wells

Grant made in 2010 Award Round

Dr Wells' team will examine the role of a family of proteins called PAK proteins, exploring how they regulate metastasis and cell survival in pancreatic cancer.

Jeff Evans

Professor Jeff Evans

Grant made in 2010 Award Round

Professor Evans is researching a new class of anti-cancer agents, that target an enzyme family called Src Kinase. The aim is to see if these agents can stop the spread of cancer following surgery.

Tony Magee

Professor Tony Magee

Grant made in 2010 Award Round

Professor Magee is investigating the role of hedgehog proteins in pancreatic cancer. These proteins direct cell growth in embryos, but are also found to be active in around 70 per cent of pancreatic tumours.

Marco Falasca

Professor Marco Falasca

Grant made in 2009 Award Round

Professor Falasca is exploring the role of a signalling molecule called p110gamma in pancreatic cancer.

Professor Yaohe Wang

Dr Yaohe Wang

Grant made in 2009 Award Round

Dr Wang has adapted the vaccinia virus, used to treat smallpox, as a potential therapeutic for treating pancreatic cancer.

Professor Lindy Durrant

Professor Lindy Durrant

Grant made in 2009 Award Round

This research aims to screen and select antibodies to tumour glycolipids that will lead to novel cancer therapeutics.